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P5C3 had the most potent neutralizing activity against 2019-nCoV Spike-coated pseudoviruses, with an EC 80 value of 0.021 μg/mL (Figures 2A and 2B).It displayed equally strong neutralization of all tested Spike mutations, including the E484K substitution that is a key mutation found in B.1.351, P.1, and the new B1.526 variant identified in New York.
Jim Yong Kim, MD, PhD; Chairman and Professor of Medicine; Department of Social Medicine, Harvard Medical School; Former Director, World Health Organization (WHO) HIV/AIDS Unit; …
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